Dolphins vs Patriots Week 1 Picks and Predictions: Pats D Will Shine In Season Opener

A vital game in the AFC East opens the 2021 NFL betting schedule when the Miami Dolphins come to Foxborough to face the New England Patriots in Week 1.

These divisional rivals are likely chasing Buffalo in the standings and find themselves in a race for second place right out of the gate, with bookies setting the Patriots as 2.5-point favorites for this season opener.

Two young former Alabama quarterbacks share the spotlight, with Miami leaning on Tua Tagovailoa and New England opting to start rookie Mac Jones. These are our free NFL picks and predictions for Dolphins at Patriots on Sunday, September 12 with kickoff at 4:25 p.m. ET.

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